What is Naloxone-ZN solution (Naloxone) used for?

Naloxone is an opiate antagonist to be used with medical intervention in cases of known or suspected opioid overdose (narcotic overdose). It is also used post-surgery when opiates have been used to reverse their effects.

How should I use Naloxone-ZN solution (Naloxone)?

Naloxone is liquid medication for injection. It should be injected intramuscularly (into a muscle), intravenously (into a vein) or subcutaneously (under the skin). Read the instructions thoroughly so you know how to perform the injection if needed.

Medical help must be obtained after receiving Naloxone injections. Make sure the medical professional is aware that naloxone has been given.

Naloxone should only be used in an emergency where narcotic overdose is known or suspected.

Continue to watch the patient after the first injection. If signs of overdose do not subside, you may need to give repeated injections every two to three minutes.

What are the side effects of Naloxone-ZN solution (Naloxone)?

Naloxone reverses the effects of opioids. As a result it will result in side effects very similar to opioid withdrawal. Side effects the patient may show include:

• nausea
• vomiting
• diarrhea
• stomach pain
• fever
• sweating
• body aches
• weakness
• tremors
• fast heart rate
• pounding heartbeats
• increased blood pressure
• feeling nervous, restless, or irritable
• goosebumps
• shivering
• runny nose
• yawning
• seizures
• crying
• stiffness
• overactive reflexes

The patient may also experience tachycardia, hypotension, hypertension, dizziness and headaches as a result of Naloxone.

Please Note

Naloxone slow reaction times and decrease alertness. Activities needing concentration and alertness should not be performed.

Narcotic pain killers will be adversely affected by Naloxone.

It has not been established if Naloxone for use by pregnant and breastfeeding women.

People with heart disease may experience complications after taking Naloxone.